アカゲザルの特異的神経回路の操作に成功。玉川大学の坂上先生、小口先生との共同研究です

In order to validate a previously inferred function of the lateral prefrontal cortex (LPFC)-caudate nucleus (CdN) pathway in humans in inhibitory control and working memory, Oguchi et al used pathway-selective chemogenetic manipulation of neural activity in macaques. By suppressing pathway-specific neural activity and observing resultant behavioural changes, they provided evidence that the LPFC-CdN pathway does indeed play a role in inhibitory control.